ASIC1a affects hypothalamic signaling and regulates the daily rhythm of body temperature in mice
Abstract The body temperature of mice is higher at night than during the day. We show here that global deletion of acid-sensing ion channel 1a (ASIC1a) results in lower body temperature during a part of the night. ASICs are pH sensors that modulate neuronal activity. The deletion of ASIC1a decreased...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-08-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-023-05221-2 |