Inhibition of NUCB2 suppresses the proliferation, migration, and invasion of rheumatoid arthritis synovial fibroblasts from patients with rheumatoid arthritis in vitro

Inhibition of NUCB2 suppresses the proliferation, migration, and invasion of rheumatoid arthritis synovial fibroblasts from patients with rheumatoid arthritis in vitro

Abstract Rheumatoid arthritis (RA) is an autoimmune polyarthritis in which synovial fibroblasts (SF) play a major role in cartilage and bone destruction through tumorlike proliferation, migration, and invasion. Nesfatin-1, an 82-amino-acid-long peptide discovered by Oh-I in 2006, is derived from the...

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Bibliographic Details
Main Authors: Shuo Zhang, Tao Zhang, Yayun Xu, Genxiang Rong, Juehua Jing
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Rheumatoid arthritis
Synovial fibroblast
Nucleobindin-2
Synovium
Proliferation
Migration
Online Access:https://doi.org/10.1186/s13018-022-03453-2

Internet

https://doi.org/10.1186/s13018-022-03453-2

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