Structural basis for transcription initiation by bacterial ECF σ factors

Extra-cytoplasmic function (ECF) σ factors allow bacteria to rapidly respond to stress conditions. Here the authors provide insights into the mechanism of bacterial stress-induced transcription by determining the crystal structures of the M. tuberculosis ECF σ factor bound RNA Polymerase (RNAP) holo...

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Bibliographic Details
Main Authors: Lingting Li, Chengli Fang, Ningning Zhuang, Tiantian Wang, Yu Zhang
Format: Article
Language:English
Published: Nature Portfolio 2019-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09096-y