Elucidating the diversity of malignant mesenchymal states in glioblastoma by integrative analysis

Abstract Background Multiple glioblastoma studies have described a mesenchymal (MES) state, with each study defining the MES program by distinct sets of genes and highlighting distinct functional associations, including both immune activation and suppression. These variable descriptions complicate o...

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Bibliographic Details
Main Authors: Rony Chanoch-Myers, Adi Wider, Mario L. Suva, Itay Tirosh
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Genome Medicine
Online Access:https://doi.org/10.1186/s13073-022-01109-8