Comprehensive analysis of m6A methylome alterations after azacytidine plus venetoclax treatment for acute myeloid leukemia by nanopore sequencing

Comprehensive analysis of m6A methylome alterations after azacytidine plus venetoclax treatment for acute myeloid leukemia by nanopore sequencing

N6 adenosine methylation (m6A), one of the most prevalent internal modifications on mammalian RNAs, regulates RNA transcription, stabilization, and splicing. Growing evidence has focused on the functional role of m6A regulators on acute myeloid leukemia (AML). However, the global m6A levels after az...

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Bibliographic Details
Main Authors: Zaifeng Zhang, Lili Zhang, Jiangtao Li, Ru Feng, Chang Li, Ye Liu, Gaoyuan Sun, Fei Xiao, Chunli Zhang
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Acute myeloid leukemia
N6-methyladenosine
Nanopore direct RNA-seq
Prognosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037024000539

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http://www.sciencedirect.com/science/article/pii/S2001037024000539

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