Small RNA-Mediated Epigenetic Myostatin Silencing

Myostatin (Mstn) is a secreted growth factor that negatively regulates muscle mass and is therefore a potential pharmacological target for the treatment of muscle wasting disorders such as Duchenne muscular dystrophy. Here we describe a novel Mstn blockade approach in which small interfering RNAs (s...

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Detaylı Bibliyografya
Asıl Yazarlar: Thomas C Roberts, Samir EL Andaloussi, Kevin V Morris, Graham McClorey, Matthew JA Wood
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Elsevier 2012-01-01
Seri Bilgileri:Molecular Therapy: Nucleic Acids
Konular:
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2162253116300804