Small RNA-Mediated Epigenetic Myostatin Silencing
Myostatin (Mstn) is a secreted growth factor that negatively regulates muscle mass and is therefore a potential pharmacological target for the treatment of muscle wasting disorders such as Duchenne muscular dystrophy. Here we describe a novel Mstn blockade approach in which small interfering RNAs (s...
Asıl Yazarlar: | , , , , |
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Materyal Türü: | Makale |
Dil: | English |
Baskı/Yayın Bilgisi: |
Elsevier
2012-01-01
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Seri Bilgileri: | Molecular Therapy: Nucleic Acids |
Konular: | |
Online Erişim: | http://www.sciencedirect.com/science/article/pii/S2162253116300804 |