P.17 Reduced Isometric Contractility and Isobaric Compliance of the ex vivo Thoracic Aorta of Hypertensive APP23+/− overexpressing Mice due to Serum Corticosterone Levels

Objective: Alzheimer’s disease (AD) is characterized by noticeable neuropsychiatric symptoms and cognitive decline [1]. In addition, cardiovascular disease (CVD) is a known etiological hallmark of AD pathogenesis [2]. Recent epidemiological evidence suggests an interplay between arterial stiffness (...

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Bibliographic Details
Main Authors: Jhana O. Hendrickx, Sofie De Moudt, Debby Van Dam, Guido R.Y. De Meyer, Paul Fransen
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Artery Research
Subjects:
Online Access:https://www.atlantis-press.com/article/125950053/view