Proteomic and single-cell landscape reveals novel pathogenic mechanisms of HBV-infected intrahepatic cholangiocarcinoma

Proteomic and single-cell landscape reveals novel pathogenic mechanisms of HBV-infected intrahepatic cholangiocarcinoma

Summary: Despite the epidemiological association between intrahepatic cholangiocarcinoma (ICC) and hepatitis B virus (HBV) infection, little is known about the relevant oncogenic effects. A cohort of 32 HBV-infected ICC and 89 non-HBV-ICC patients were characterized using whole-exome sequencing, pro...

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Bibliographic Details
Main Authors: Yifei Shen, Shuaishuai Xu, Chanqi Ye, Qiong Li, Ruyin Chen, Wei Wu, Qi Jiang, Yunlu Jia, Xiaochen Zhang, Longjiang Fan, Wenguang Fu, Ming Jiang, Jinzhang Chen, Michael P. Timko, Peng Zhao, Jian Ruan
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:iScience
Subjects:
Virology
Cancer
Omics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223000809

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http://www.sciencedirect.com/science/article/pii/S2589004223000809

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