Effect of sorafenib induced apoptosis and autophagy on drug resistance in HeLa cells

Objective To explore the effect of sorafenib on HeLa cell proliferation by inducing cell apoptosis and autophagy and its impact on drug resistance. Methods The drug-resistant cell strains were constructed through intermittent induction method, with concentrations of 0, 2.5, 5.0, 7.5, 10.0, 15.0, 20....

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Bibliographic Details
Main Author: YANG Kaifei, ZHU Jingge, ZHANG Yangyang, ZHAO Junguo, GAO Yuyue, HU Huanhuan, JI Guojie
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2024-04-01
Series:Jichu yixue yu linchuang
Subjects:
Online Access:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2024-44-4-467.pdf