Results of the phase IIa study to evaluate the efficacy and safety of rezivertinib (BPI-7711) for the first-line treatment of locally advanced or metastatic/recurrent NSCLC patients with EGFR mutation from a phase I/IIa study

Results of the phase IIa study to evaluate the efficacy and safety of rezivertinib (BPI-7711) for the first-line treatment of locally advanced or metastatic/recurrent NSCLC patients with EGFR mutation from a phase I/IIa study

Abstract Background Rezivertinib (BPI-7711) is a novel third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). This phase IIa study was part of a phase I/IIa study (NCT03386955), aimed to evaluate the efficacy and safety of rezivertinib as the first-line treatment f...

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Bibliographic Details
Main Authors: Yuankai Shi, Jianying Zhou, Yanqiu Zhao, Bo Zhu, Liangming Zhang, Xingya Li, Jian Fang, Jianhua Shi, Zhixiang Zhuang, Sheng Yang, Donglin Wang, Huiqing Yu, Longzhen Zhang, Rongsheng Zheng, Michael Greco, Tingting Wang
Format: Article
Language:English
Published: BMC 2023-01-01
Series:BMC Medicine
Subjects:
Rezivertinib
BPI-7711
NSCLC
EGFR mutation
Third-generation EGFR TKI
Online Access:https://doi.org/10.1186/s12916-022-02692-8

Internet

https://doi.org/10.1186/s12916-022-02692-8

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