Progressive Proteome Changes in the Myocardium of a Pig Model for Duchenne Muscular Dystrophy

Summary: Duchenne muscular dystrophy (DMD), caused by mutations in the dystrophin gene, is characterized by progressive muscle weakness. Even though DMD manifests first in skeletal muscle, heart failure is a major cause of death in late-stage DMD. To get insights into DMD-associated cardiomyopathy,...

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Bibliographic Details
Main Authors: Hathaichanok Tamiyakul, Elisabeth Kemter, Miwako Kösters, Stefanie Ebner, Andreas Blutke, Nikolai Klymiuk, Florian Flenkenthaler, Eckhard Wolf, Georg J. Arnold, Thomas Fröhlich
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220307082