Germline and somatic mutations of multi-gene panel in Chinese patients with epithelial ovarian cancer: a prospective cohort study

Germline and somatic mutations of multi-gene panel in Chinese patients with epithelial ovarian cancer: a prospective cohort study

Abstract Background Multiple targeted gene sequencing is seldom performed in both germline and somatic testing for ovarian cancer. This study is to evaluate the specific genetic alterations, including both somatic and germline mutations, in Chinese patients with epithelial ovarian cancer (EOC) in a...

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Bibliographic Details
Main Authors: Wenhui Li, Di Shao, Lei Li, Ming Wu, Shuiqing Ma, Xianjie Tan, Sen Zhong, Fengming Guo, Zhe Wang, Mingzhi Ye
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Journal of Ovarian Research
Subjects:
Epithelial ovarian cancer
Next-generation sequencing
Germline mutation
Somatic mutation
Homologous recombination deficiency
Online Access:http://link.springer.com/article/10.1186/s13048-019-0560-y

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http://link.springer.com/article/10.1186/s13048-019-0560-y

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