The RNA m6A writer METTL3 in tumor microenvironment: emerging roles and therapeutic implications

The RNA m6A writer METTL3 in tumor microenvironment: emerging roles and therapeutic implications

The tumor microenvironment (TME) is a heterogeneous ecosystem comprising cancer cells, immune cells, stromal cells, and various non-cellular components, all of which play critical roles in controlling tumor progression and response to immunotherapies. Methyltransferase-like 3 (METTL3), the core comp...

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Bibliographic Details
Main Authors: Weiqi Su, Lin Che, Wenting Liao, Huilin Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
methyltransferase-like 3 (METTL3)
N6-methyladenosine (m6A)
tumor-infiltrating immune cells (TICs)
small molecular inhibitors
cancer immunotherapy
immune checkpoint inhibitors (ICI)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1335774/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1335774/full

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