Sputum bacterial load and bacterial composition correlate with lung function and are altered by long-term azithromycin treatment in children with HIV-associated chronic lung disease

Sputum bacterial load and bacterial composition correlate with lung function and are altered by long-term azithromycin treatment in children with HIV-associated chronic lung disease

Abstract Background Long-term azithromycin (AZM) treatment reduces the frequency of acute respiratory exacerbation in children and adolescents with HIV-associated chronic lung disease (HCLD). However, the impact of this treatment on the respiratory bacteriome is unknown. Method African children with...

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Bibliographic Details
Main Authors: Regina E. Abotsi, Felix S. Dube, Andrea M. Rehman, Shantelle Claassen-Weitz, Yao Xia, Victoria Simms, Kilaza S. Mwaikono, Sugnet Gardner-Lubbe, Grace McHugh, Lucky G. Ngwira, Brenda Kwambana-Adams, Robert S. Heyderman, Jon Ø. Odland, Rashida A. Ferrand, Mark P. Nicol, The BREATHE study team
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Microbiome
Subjects:
Africa
Bacteriome
Microbiome
HIV
Haemophilus
Moraxella
Online Access:https://doi.org/10.1186/s40168-023-01460-x

Internet

https://doi.org/10.1186/s40168-023-01460-x

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