Interferons reshape the 3D conformation and accessibility of macrophage chromatin

Interferons reshape the 3D conformation and accessibility of macrophage chromatin

Summary: Engagement of macrophages in innate immune responses is directed by type I and type II interferons (IFN-I and IFN-γ, respectively). IFN triggers drastic changes in cellular transcriptomes, executed by JAK-STAT signal transduction and the transcriptional control of interferon-stimulated gene...

Full description

Bibliographic Details
Main Authors: Ekaterini Platanitis, Stephan Gruener, Aarathy Ravi Sundar Jose Geetha, Laura Boccuni, Alexander Vogt, Maria Novatchkova, Andreas Sommer, Iros Barozzi, Mathias Müller, Thomas Decker
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:iScience
Subjects:
Molecular biology
Molecular mechanism of gene regulation
Epigenetics
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222001109

Internet

http://www.sciencedirect.com/science/article/pii/S2589004222001109

Similar Items