CD73 mitigates ZEB1 expression in papillary thyroid carcinoma

CD73 mitigates ZEB1 expression in papillary thyroid carcinoma

Abstract Background ZEB1, a core transcription factor involved in epithelial-mesenchymal transition (EMT), is associated with aggressive cancer cell behavior, treatment resistance, and poor prognosis across various tumor types. Similarly, the expression and activity of CD73, an ectonucleotidase impl...

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Bibliographic Details
Main Authors: Samlai Vedovatto, Fernanda Dittrich Oliveira, Luiza Cherobini Pereira, Thamiris Becker Scheffel, Liziane Raquel Beckenkamp, Ana Paula Santin Bertoni, Márcia Rosângela Wink, Guido Lenz
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Cell Communication and Signaling
Subjects:
CD73
ZEB1
Papillary thyroid carcinoma
Epithelial-mesenchymal plasticity
Adenosinergic signaling
Online Access:https://doi.org/10.1186/s12964-024-01522-z

Internet

https://doi.org/10.1186/s12964-024-01522-z

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