Polymorphisms of arylamine N-acetyltransferase2 and risk of lung and colorectal cancer

Polymorphisms of arylamine N-acetyltransferase2 and risk of lung and colorectal cancer

The arylamine N-acetyltransferase 2 (NAT2) enzymes detoxify a wide range of naturally occurring xenobiotics including carcinogens and drugs. Point mutations in the NAT2 gene result in the variant alleles M1 (NAT2 *5A), M2 (NAT2*6A), M3 (NAT2*7) and M4 (NAT2 *14A) from the wild-type WT (NAT2 *4) alle...

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Bibliographic Details
Main Authors: Amjad Mahasneh, Amal Jubaili, Ahmed El Bateiha, Mohammad Al-Ghazo, Ismail Matalka, Mousa Malkawi
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2012-01-01
Series:Genetics and Molecular Biology
Subjects:
NAT2
lung cancer
colorectal cancer
polymorphisms
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000500003

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000500003

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