TRPV4 enhances the synthesis of fatty acids to drive the progression of ovarian cancer through the calcium-mTORC1/SREBP1 signaling pathway

Summary: Transient receptor potential vanilloid 4 (TRPV4) is a nonselective cation channel activated by various stimuli, such as heat. A recent study reported that high expression of TRPV4 predicted a poor prognosis in ovarian cancer patients. This study demonstrated that TRPV4 was highly expressed...

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Bibliographic Details
Main Authors: Lan Lin, Xiao Li, Ai-Jia Wu, Jia-bin Xiu, Yu-Zheng Gan, Xiao-mei Yang, Zhi-Hong Ai
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223023039