Divergent regulation of basement membrane trafficking by human macrophages and cancer cells

Cancer cells and macrophages can infiltrate and remodel the extracellular matrix (ECM). Here, by using native basement membrane-interstitial matrix explants as model and live cell confocal imaging, the authors reveal divergent mechanisms used by cancer cells and macrophages to penetrate native basem...

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Bibliographic Details
Main Authors: Julian C. Bahr, Xiao-Yan Li, Tamar Y. Feinberg, Long Jiang, Stephen J. Weiss
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34087-x