Altered placental expression of PAPPA2 does not affect birth weight in mice

<p>Abstract</p> <p>Background</p> <p>Pregnancy-associated plasma protein A2 (PAPPA2) is an insulin-like growth factor binding protein (IGFBP) protease expressed in the placenta and upregulated in pregnancies complicated by pre-eclampsia. The mechanism linking PAPPA2 exp...

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Bibliographic Details
Main Authors: Christians Julian K, Wagner Pamela K
Format: Article
Language:English
Published: BMC 2010-07-01
Series:Reproductive Biology and Endocrinology
Online Access:http://www.rbej.com/content/8/1/90