Kinetic modelling of β‐cell metabolism reveals control points in the insulin‐regulating pyruvate cycling pathways
Abstract Insulin, a key hormone in the regulation of glucose homoeostasis, is secreted by pancreatic β‐cells in response to elevated glucose levels. Insulin is released in a biphasic manner in response to glucose metabolism in β‐cells. The first phase of insulin secretion is triggered by an increase...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-12-01
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| Series: | IET Systems Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1049/syb2.12077 |