Synthesis and Properties of Sucrose- and Lactose-Based Aromatic Ester Surfactants as Potential Drugs Permeability Enhancers

Synthesis and Properties of Sucrose- and Lactose-Based Aromatic Ester Surfactants as Potential Drugs Permeability Enhancers

The delivery of therapeutics across biological membranes (e.g., mucosal barriers) by avoiding invasive routes (e.g., injection) remains a challenge in the pharmaceutical field. As such, there is the need to discover new compounds that act as drug permeability enhancers with a favorable toxicological...

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Bibliographic Details
Main Authors: Michele Verboni, Diego Romano Perinelli, Carol Yingshan Qiu, Mattia Tiboni, Annalisa Aluigi, Simone Lucarini, Jenny K. W. Lam, Andrea Duranti
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pharmaceuticals
Subjects:
glycolipids
sucrose monoesters
lactose monoesters
sugar-based surfactants
biocompatibility studies
permeability enhancers
Online Access:https://www.mdpi.com/1424-8247/16/2/223

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https://www.mdpi.com/1424-8247/16/2/223

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