Elevated Expression of lncRNA MEG3 Induces Endothelial Dysfunction on HUVECs of IVF Born Offspring via Epigenetic Regulation

Elevated Expression of lncRNA MEG3 Induces Endothelial Dysfunction on HUVECs of IVF Born Offspring via Epigenetic Regulation

Cardiovascular dysfunction in children born after in vitro fertilization (IVF) has been of great concern, the potential molecular mechanisms for such long-term outcomes are still unknown. Here, we found that systolic blood pressure was a little higher in IVF born offspring at 2 years old compared to...

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Bibliographic Details
Main Authors: Ying Jiang, Hong Zhu, Hong Chen, Yi-Chen Yu, Ye-Tao Xu, Fang Liu, Sai-Nan He, Matthew Sagnelli, Yi-Min Zhu, Qiong Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
long non-coding RNA
endothelial dysfunction
IVF
epigenetic
fetal-origin adult diseases
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.717729/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2021.717729/full

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