Predicting conserved protein motifs with Sub-HMMs

<p>Abstract</p> <p>Background</p> <p>Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is the difficulty to pinpoint their much shorter functional sub-feature...

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Bibliographic Details
Main Authors: Girke Thomas, Shelton Christian R, Horan Kevin
Format: Article
Language:English
Published: BMC 2010-04-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/205