Phenotypic Screens Identify Parasite Genetic Factors Associated with Malarial Fever Response in <named-content content-type="genus-species">Plasmodium falciparum</named-content><italic toggle="yes">piggyBac</italic> Mutants

Phenotypic Screens Identify Parasite Genetic Factors Associated with Malarial Fever Response in <named-content content-type="genus-species">Plasmodium falciparum</named-content><italic toggle="yes">piggyBac</italic> Mutants

ABSTRACT Malaria remains one of the most devastating parasitic diseases worldwide, with 90% of the malaria deaths in Africa in 2013 attributable to Plasmodium falciparum. The clinical symptoms of malaria include cycles of fever, corresponding to parasite rupture from red blood cells every 48 h. Para...

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Bibliographic Details
Main Authors: Phaedra Thomas, Jennifer Sedillo, Jenna Oberstaller, Suzanne Li, Min Zhang, Naresh Singh, Chengqi C. Q. Wang, Kenneth Udenze, Rays H. Y. Jiang, John H. Adams
Format: Article
Language:English
Published: American Society for Microbiology 2016-10-01
Series:mSphere
Subjects:
forward genetics
heat shock
phenotype screen
piggyBac
transposon-mediated mutagenesis
virulence factors
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00273-16

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https://journals.asm.org/doi/10.1128/mSphere.00273-16

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