GMP-compatible and xeno-free cultivation of mesenchymal progenitors derived from human-induced pluripotent stem cells

GMP-compatible and xeno-free cultivation of mesenchymal progenitors derived from human-induced pluripotent stem cells

Abstract Background Human mesenchymal stem cells are a strong candidate for cell therapies owing to their regenerative potential, paracrine regulatory effects, and immunomodulatory activity. Yet, their scarcity, limited expansion potential, and age-associated functional decline restrict the ability...

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Bibliographic Details
Main Authors: Madison McGrath, Edmund Tam, Martina Sladkova, Athbah AlManaie, Matthew Zimmer, Giuseppe Maria de Peppo
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Stem Cell Research & Therapy
Subjects:
Cell therapy
Fetal bovine serum
Good Manufacturing Practice
Human platelet lysate
Induced pluripotent stem cell
Mesenchymal stem cell
Online Access:http://link.springer.com/article/10.1186/s13287-018-1119-3

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http://link.springer.com/article/10.1186/s13287-018-1119-3

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