Old and New Beta-Lactamase Inhibitors: Molecular Structure, Mechanism of Action, and Clinical Use

The β-lactams have a central place in the antibacterial armamentarium, but the increasing resistance to these drugs, especially among Gram-negative bacteria, is becoming one of the major threats to public health worldwide. Treatment options are limited, and only a small number of novel antibiotics a...

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Bibliographic Details
Main Authors: Davide Carcione, Claudia Siracusa, Adela Sulejmani, Valerio Leoni, Jari Intra
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/10/8/995