The Targeting of Native Proteins to the Endoplasmic Reticulum-Associated Degradation (ERAD) Pathway: An Expanding Repertoire of Regulated Substrates

All proteins are subject to quality control processes during or soon after their synthesis, and these cellular quality control pathways play critical roles in maintaining homeostasis in the cell and in organism health. Protein quality control is particularly vital for those polypeptides that enter t...

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Bibliographic Details
Main Authors: Deepa Kumari, Jeffrey L. Brodsky
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/11/8/1185