Rationale of using the dual chemokine receptor CCR2/CCR5 inhibitor cenicriviroc for the treatment of COVID-19.

Coronavirus Disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has created a global pandemic infecting over 230 million people and costing millions of lives. Therapies to attenuate severe disease are desperately needed. Cenicriviroc (CVC), a C-C chemokin...

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Bibliographic Details
Main Authors: Daniel Clark Files, Frank Tacke, Alexandra O'Sullivan, Patrick Dorr, William G Ferguson, William G Powderly
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-06-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010547