Histological and Immunohistochemical Analysis of the Effects of Topical Melatonin Treatment Associated with Collagen Sponge and rhBMP-2 Protein on Bone Remodeling

Extensive bone defect healing is an important health issue not yet completely resolved. Different alternative treatments have been proposed but, in face of a critical bone defect, it is still very difficult to reach a complete regeneration, with the new-formed bone presenting all morphological and p...

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Bibliographic Details
Main Authors: Leticia Ferreira Montarele, Dimitrius Leonardo Pitol, Bruno Fiorelini Pereira, Sara Feldman, Valéria Paula Sassoli Fazan, João Paulo Mardegan Issa
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/12/12/1738