QishenYiqi dripping pill protects against myocardial ischemia/reperfusion injury via suppressing excessive autophagy and NLRP3 inflammasome based on network pharmacology and experimental pharmacology

QishenYiqi dripping pill protects against myocardial ischemia/reperfusion injury via suppressing excessive autophagy and NLRP3 inflammasome based on network pharmacology and experimental pharmacology

Background: Myocardial ischemia/reperfusion (I/R) injury is associated with multiple serious clinical manifestations. Autophagy is upregulated in a short period of ischemia and further enhanced during reperfusion phase, which was considered as a “double-edged sword” in the pathological process of my...

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Bibliographic Details
Main Authors: Meng Li, Yueyao Wang, Zhongwen Qi, Zhuo Yuan, Shichao Lv, Yawei Zheng, Zhipeng Yan, Mingyang Wang, Huanjie Fu, Xinbiao Fan, Nan Ji, Ming Liu, Zhuyuan Fang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Pharmacology
Subjects:
QSYQ
myocardial ischemia
reperfusion
autophagy
NLRP3 inflammasome
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.981206/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.981206/full

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