Iron limitation indirectly reduces the Escherichia coli torCAD operon expression by a reduction of molybdenum cofactor availability

Iron limitation indirectly reduces the Escherichia coli torCAD operon expression by a reduction of molybdenum cofactor availability

ABSTRACTThe expression of most molybdoenzymes in Escherichia coli has so far been revealed to be regulated by anaerobiosis and requires the presence of iron, based on the necessity of the transcription factor FNR to bind one [4Fe-4S] cluster. One exception is trimethylamine-N-oxide reductase encoded...

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Bibliographische Detailangaben
Hauptverfasser: Muhammad Abrar Hasnat, Arkadiusz Zupok, Michal Gorka, Chantal Iobbi-Nivol, Aleksandra Skirycz, Cécile Jourlin-Castelli, Frank Bier, Saloni Agarwal, Ehizode Irefo, Silke Leimkühler
Format: Artikel
Sprache:English
Veröffentlicht: American Society for Microbiology 2024-02-01
Schriftenreihe:Microbiology Spectrum
Schlagworte:
iron regulation
Escherichia coli
molybdenum cofactor
FNR
iron-sulfur cluster
anaerobic respiration
Online Zugang:https://journals.asm.org/doi/10.1128/spectrum.03480-23

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https://journals.asm.org/doi/10.1128/spectrum.03480-23

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