Intrinsic Aqueous Solubility: Mechanistically Transparent Data-Driven Modeling of Drug Substances

Intrinsic Aqueous Solubility: Mechanistically Transparent Data-Driven Modeling of Drug Substances

Intrinsic aqueous solubility is a foundational property for understanding the chemical, technological, pharmaceutical, and environmental behavior of drug substances. Despite years of solubility research, molecular structure-based prediction of the intrinsic aqueous solubility of drug substances is s...

Full description

Bibliographic Details
Main Authors: Mare Oja, Sulev Sild, Geven Piir, Uko Maran
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Pharmaceutics
Subjects:
solubility
drug substances
QSAR
QSPR
fit-for-purpose training set
multiple linear regression
Online Access:https://www.mdpi.com/1999-4923/14/10/2248

Internet

https://www.mdpi.com/1999-4923/14/10/2248

Similar Items