Tanshinone I alleviates steroid-induced osteonecrosis of femoral heads and promotes angiogenesis: in vivo and in vitro studies

Tanshinone I alleviates steroid-induced osteonecrosis of femoral heads and promotes angiogenesis: in vivo and in vitro studies

Abstract Background The impaired blood supply to the bones is an important pathological feature of steroid-induced osteonecrosis of the femoral head (SIONFH). Danshen is a Chinese herb that shows therapeutic effects on SIONFH, but the effects of one of its major bioactive constituents, Tanshinone I...

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Bibliographic Details
Main Authors: Kai Sun, Yuman Xue, Xin Zhang, Xiaodong Li, Jun Zhao, Xilin Xu, Xiaofeng Zhang, Fubiao Yang
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Steroid
Osteonecrosis of the femoral head
Tanshinone I
Angiogenesis
SRY-box transcription factor 11
Online Access:https://doi.org/10.1186/s13018-023-03934-y

Internet

https://doi.org/10.1186/s13018-023-03934-y

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