Exogenous IL-17A Alleviates Social Behavior Deficits and Increases Neurogenesis in a Murine Model of Autism Spectrum Disorders

Exogenous IL-17A Alleviates Social Behavior Deficits and Increases Neurogenesis in a Murine Model of Autism Spectrum Disorders

Among the proposed mechanisms for autism spectrum disorders (ASD) is immune dysregulation. The proinflammatory cytokine Interleukine-17A (IL-17A) was shown to play a key role in mediating immune-related neurodevelopmental impairment of social behavior. Nevertheless, post-developmental administration...

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Bibliographic Details
Main Authors: Yehoshua Willinger, Daniella R. Friedland Cohen, Gadi Turgeman
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:International Journal of Molecular Sciences
Subjects:
autism spectrum disorder (ASD)
hippocampal neurogenesis
IL-17A
social behavior
Online Access:https://www.mdpi.com/1422-0067/25/1/432

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https://www.mdpi.com/1422-0067/25/1/432

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