The key cellular senescence related molecule RRM2 regulates prostate cancer progression and resistance to docetaxel treatment

The key cellular senescence related molecule RRM2 regulates prostate cancer progression and resistance to docetaxel treatment

Abstract Background Prostate cancer is a leading cause of cancer-related deaths among men worldwide. Docetaxel chemotherapy has proven effective in improving overall survival in patients with castration-resistant prostate cancer (CRPC), but drug resistance remains a considerable clinical challenge....

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Bibliographic Details
Main Authors: Bisheng Cheng, Lingfeng Li, Yongxin Wu, Tianlong Luo, Chen Tang, Qiong Wang, Qianghua Zhou, Jilin Wu, Yiming Lai, Dingjun Zhu, Tao Du, Hai Huang
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Cell & Bioscience
Subjects:
RRM2
Prostate cancer
Chemotherapy
Docetaxel
Oncology
Online Access:https://doi.org/10.1186/s13578-023-01157-6

Internet

https://doi.org/10.1186/s13578-023-01157-6

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