What exactly does the PfK13 C580Y mutation in Plasmodium falciparum influence?

What exactly does the PfK13 C580Y mutation in Plasmodium falciparum influence?

Abstract Background The emergence and spread of artemisinin resistance threaten global malaria control and elimination goals, and encourage research on the mechanisms of drug resistance in malaria parasites. Mutations in Plasmodium falciparum Kelch 13 (PfK13) protein are associated with artemisinin...

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Bibliographic Details
Main Authors: Wenwen Si, Yuemeng Zhao, Xixi Qin, Yixuan Huang, Jing Yu, Xiao Liu, Yanna Li, Xiaoli Yan, Qingfeng Zhang, Jun Sun
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Parasites & Vectors
Subjects:
Artemisinin resistance
PfK13 mutation
P. falciparum 3D7C580Y
Transcriptome
Iron supply
Merozoite number
Online Access:https://doi.org/10.1186/s13071-023-06024-4

Internet

https://doi.org/10.1186/s13071-023-06024-4

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