Overexpression of TGF-ß1 in macrophages reduces and stabilizes atherosclerotic plaques in ApoE-deficient mice.

Overexpression of TGF-ß1 in macrophages reduces and stabilizes atherosclerotic plaques in ApoE-deficient mice.

Although macrophages represent the hallmark of both human and murine atherosclerotic lesions and have been shown to express TGF-ß1 (transforming growth factor β1) and its receptors, it has so far not been experimentally addressed whether the pleiotropic cytokine TGF-ß1 may influence atherogenesis by...

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Bibliographic Details
Main Authors: Kurt Reifenberg, Fei Cheng, Carolin Orning, Jeanine Crain, Ines Küpper, Elena Wiese, Martina Protschka, Manfred Blessing, Karl J Lackner, Michael Torzewski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22829904/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22829904/?tool=EBI

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