Apurinic/apyrimidinic endonuclease 1 is associated with poor prognosis after curative resection followed by adjuvant chemotherapy in patients with stage III colon cancer

Purpose Apurinic/apyrimidinic endonuclease 1 (APE1) is a key enzyme involved in the base excision repair pathway. It also has redox activity and maintains various transcription factors in an active reduced state. APE1 may be associated with chemoresistance. In the present study, we first investigate...

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Bibliographic Details
Main Authors: Ji Hyeong Song, Myung Sun Lee, Eun Young Cha, Kyung Ha Lee, Ji Yeon Kim, Jin Soo Kim
Format: Article
Language:English
Published: Korean Society of Surgical Oncology 2022-06-01
Series:Korean Journal of Clinical Oncology
Subjects:
Online Access:http://www.kjco.org/upload/kjco-18-1-1.pdf