A Global Gene Body Methylation Measure Correlates Independently with Overall Survival in Solid Cancer Types

A Global Gene Body Methylation Measure Correlates Independently with Overall Survival in Solid Cancer Types

Epigenetics, CpG methylation of CpG islands (CGI) and gene bodies (GBs), plays an important role in gene regulation and cancer biology, the former established as a transcription regulator. Genome wide CpG methylation, summarized over GBs and CGIs, was analyzed for impact on overall survival (OS) in...

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Bibliographic Details
Main Authors: Dietmar Pils, Elisabeth Steindl, Anna Bachmayr-Heyda, Sabine Dekan, Stefanie Aust
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cancers
Subjects:
gene body
DNA methylation
CGI
overall survival
epigenetics
CpG island
Online Access:https://www.mdpi.com/2072-6694/12/8/2257

Internet

https://www.mdpi.com/2072-6694/12/8/2257

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