Utility of five commonly used immunohistochemical markers TTF‐1, Napsin A, CK7, CK5/6 and P63 in primary and metastatic adenocarcinoma and squamous cell carcinoma of the lung: a retrospective study of 246 fine needle aspiration cases

Utility of five commonly used immunohistochemical markers TTF‐1, Napsin A, CK7, CK5/6 and P63 in primary and metastatic adenocarcinoma and squamous cell carcinoma of the lung: a retrospective study of 246 fine needle aspiration cases

Abstract BackgroundFine needle aspiration (FNA) biopsy plays a critical role in the diagnosis and staging of lung primary and metastatic lung carcinoma. Accurate subclassification of adenocarcinoma (ADC) and/or squamous cell carcinoma (SqCC) is crucial for the targeted therapy. However, the distinct...

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Bibliographic Details
Main Authors: Grzegorz T Gurda, Lei Zhang, Yuting Wang, Li Chen, Susan Geddes, William C Cho, Frederic Askin, Edward Gabrielson, Qing Kay Li
Format: Article
Language:English
Published: Wiley 2015-12-01
Series:Clinical and Translational Medicine
Subjects:
Non‐small cell lung carcinoma (NSCLC)
Fine needle aspiration (FNA) cytology
Cytopathology
Immunohistochemical (IHC) marker
TTF‐1
Napsin A
Online Access:https://doi.org/10.1186/s40169-015-0057-2

Internet

https://doi.org/10.1186/s40169-015-0057-2

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