Identification and characterization of the pathogenic potential of phenol-soluble modulin toxins in the mouse commensal Staphylococcus xylosus

In contrast to the virulent human skin commensal Staphylococcus aureus, which secretes a plethora of toxins, other staphylococci have much reduced virulence. In these species, commonly the only toxins are those of the phenol-soluble modulin (PSM) family. PSMs are species-specific and have only been...

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Main Authors: Kunal Reshamwala, Gordon Y. C. Cheung, Roger C. Hsieh, Ryan Liu, Hwang-Soo Joo, Yue Zheng, Justin S. Bae, Thuan H. Nguyen, Amer E. Villaruz, Alfonso S. Gozalo, William R. Elkins, Michael Otto
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.999201/full