Sumoylation of hypoxia-inducible factor-1α ameliorates failure of brain stem cardiovascular regulation in experimental brain death.

Sumoylation of hypoxia-inducible factor-1α ameliorates failure of brain stem cardiovascular regulation in experimental brain death.

One aspect of brain death is cardiovascular deregulation because asystole invariably occurs shortly after its diagnosis. A suitable neural substrate for mechanistic delineation of this aspect of brain death resides in the rostral ventrolateral medulla (RVLM). RVLM is the origin of a life-and-death s...

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Bibliographic Details
Main Authors: Julie Y H Chan, Ching-Yi Tsai, Carol H Y Wu, Faith C H Li, Kuang-Yu Dai, Enya Y H Sun, Samuel H H Chan, Alice Y W Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3048406?pdf=render

Internet

http://europepmc.org/articles/PMC3048406?pdf=render

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