Understanding the roles and regulation patterns of circRNA on its host gene in tumorigenesis and tumor progression

Understanding the roles and regulation patterns of circRNA on its host gene in tumorigenesis and tumor progression

Abstract Circular RNAs (circRNAs) are a novel type of endogenous non-coding RNAs, which are covalently closed loop structures formed by precursor mRNAs (pre-mRNAs) through back-splicing. CircRNAs are abnormally expressed in many tumors, and play critical roles in a variety of tumors as oncogenes or...

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Bibliographic Details
Main Authors: Jianxia Wei, Mengna Li, Changning Xue, Shipeng Chen, Lemei Zheng, Hongyu Deng, Faqing Tang, Guiyuan Li, Wei Xiong, Zhaoyang Zeng, Ming Zhou
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
CircRNA
Host gene
Regulation
Tumorigenesis
Tumor progression
Online Access:https://doi.org/10.1186/s13046-023-02657-6

Internet

https://doi.org/10.1186/s13046-023-02657-6

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