A Novel Type of Non-coding RNA, nc886, Implicated in Tumor Sensing and Suppression

nc886 (=vtRNA2-1, pre-miR-886, or CBL3) is a newly identified non-coding RNA (ncRNA) that represses the activity of protein kinase R (PKR). nc886 is transcribed by RNA polymerase III (Pol III) and is intriguingly the first case of a Pol III gene whose expression is silenced by CpG DNA hypermethylati...

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Bibliographic Details
Main Author: Yong Sun Lee
Format: Article
Language:English
Published: Korea Genome Organization 2015-06-01
Series:Genomics & Informatics
Subjects:
Online Access:http://genominfo.org/upload/pdf/gni-13-26.pdf