Peptidomimetics and Their Applications for Opioid Peptide Drug Discovery

Peptidomimetics and Their Applications for Opioid Peptide Drug Discovery

Despite various advantages, opioid peptides have been limited in their therapeutic uses due to the main drawbacks in metabolic stability, blood-brain barrier permeability, and bioavailability. Therefore, extensive studies have focused on overcoming the problems and optimizing the therapeutic potenti...

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Bibliographic Details
Main Author: Yeon Sun Lee
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biomolecules
Subjects:
opioid receptors
analgesic drugs
bioavailability
peptidomimetic
peptide backbone modifications
locally constrained peptides
Online Access:https://www.mdpi.com/2218-273X/12/9/1241

Internet

https://www.mdpi.com/2218-273X/12/9/1241

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