The transcriptional repressor protein NsrR senses nitric oxide directly via a [2Fe-2S] cluster.

The regulatory protein NsrR, a member of the Rrf2 family of transcription repressors, is specifically dedicated to sensing nitric oxide (NO) in a variety of pathogenic and non-pathogenic bacteria. It has been proposed that NO directly modulates NsrR activity by interacting with a predicted [Fe-S] cl...

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Bibliographic Details
Main Authors: Nicholas P Tucker, Matthew G Hicks, Thomas A Clarke, Jason C Crack, Govind Chandra, Nick E Le Brun, Ray Dixon, Matthew I Hutchings
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2577008?pdf=render