Fides: Reliable trust-region optimization for parameter estimation of ordinary differential equation models.

Ordinary differential equation (ODE) models are widely used to study biochemical reactions in cellular networks since they effectively describe the temporal evolution of these networks using mass action kinetics. The parameters of these models are rarely known a priori and must instead be estimated...

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Bibliographic Details
Main Authors: Fabian Fröhlich, Peter K Sorger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-07-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010322