Ensemble machine learning identifies genetic loci associated with future worsening of disability in people with multiple sclerosis

Abstract Limited studies have been conducted to identify and validate multiple sclerosis (MS) genetic loci associated with disability progression. We aimed to identify MS genetic loci associated with worsening of disability over time, and to develop and validate ensemble genetic learning model(s) to...

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Bibliographic Details
Main Authors: Valery Fuh-Ngwa, Yuan Zhou, Phillip E. Melton, Ingrid van der Mei, Jac C. Charlesworth, Xin Lin, Amin Zarghami, Simon A. Broadley, Anne-Louise Ponsonby, Steve Simpson-Yap, Jeannette Lechner-Scott, Bruce V. Taylor
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-23685-w