Genetic Analysis and Species Specific Amplification of the Artemisinin Resistance-Associated Kelch Propeller Domain in P. falciparum and P. vivax.

Plasmodium falciparum resistance to artemisinin has emerged in the Greater Mekong Subregion and now poses a threat to malaria control and prevention. Recent work has identified mutations in the kelch propeller domain of the P. falciparum K13 gene to be associated artemisinin resistance as defined by...

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Bibliographic Details
Main Authors: Eldin Talundzic, Stella M Chenet, Ira F Goldman, Dhruviben S Patel, Julia A Nelson, Mateusz M Plucinski, John W Barnwell, Venkatachalam Udhayakumar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4546394?pdf=render